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ArARe e y

May 2024


When it comes to aging, a significant factor that leads to wrinkles, fine lines, and joint pain is due to inadequate collagen levels. Collagen is the main structural protein found in your skin and other connective tissue. Collagen literally holds our bodies together. An easy way to remember what collagen does is to look at the Greek prefix ‘kolla’ which means glue.


Increased fibroblast proliferation is just one benefit of LED red light therapy.

Fibroblasts make collagen fibers, so it stands to reason that the more, and healthier, fibroblasts we have in the skin, the more and better collagen fibers are made. And as we all know, collagen synthesis and maintenance is the bedrock of anti-aging.


Collagen is a key to longevity.


Healthy collagen levels are what give us a glowing complexion, firm skin, strong nails, dense bones, and healthy hair. It is also essential in keeping muscles, joints, and tendons in healthy working order. Simply put, the more our bodies produce collagen, the better we’ll look and feel as we age and attempt to delay tissue and cell degeneration.


Signs of Aging 

Fibroblast cells are responsible for producing collagen and elastin, the two most common proteins in connective tissue. However, as we age, our fibroblast cells become compromised resulting in lower levels of these proteins. We might start noticing decreased elasticity in our skin, wrinkles, and our joints may not move as freely as they used to. This is because lower levels of collagen lead to breakdowns in cartilage which can cause inflammation, soreness, stiffness, arthritis, and prolonged recovery time after physical activity.


Other common signs of aging can include:

  • Skin and tissue deterioration

  • Melasma

  • Arthritis

  • Inflammation

  • Chronic joint and muscle pain

  • Keratosis


If you’re experiencing one or more of these signs, then it could be an indicator your collagen levels are deficient.


The Benefits of LED Therapy

What the Research Says:
The depth of each wavelength adopted in LED therapy (blue, red, and near infrared) have differing primary targets and photoreactions in the target cells through photon absorption, intracellular signal transduction and finally the cellular photo-response. Visible wavelengths stimulate cellular metabolism by triggering intracellular photobiochemical reactions. The observed effects include increased ATP, an organic chemical that provides energy, modulation of reactive oxidative species (ROS), alteration of collagen synthesis, stimulation of angiogenesis and increased blood flow. Research also demonstrated the increase in the production of multiple growth factors and the inhibition of apoptosis or “cell death”. All studies have demonstrated a statistically significant improvement in skin rejuvenation, as well as enhancing existing rejuvenation treatments (3,4) Clinical studies in the use of red LED (630-700nm) on human and animal tissue, have demonstrated it activates fibroblast growth factors, increasing type 1 procollagen, an increase in Matrix metalloproteinase-9 (MMP-9) and a decrease in MMP-1. (2). These result in the reduction of fine lines and wrinkles, improvement in photo-aging, a decrease in melanin and softer, smoother healthier looking skin. Skin analysis studies reveal an increased collagen density in the papillary and upper reticular dermis with the collagen bundles more packed and well organized. The thickness was observed to be greater than when evaluated before red LED treatment.


Anti-Aging Treatment with LED Light Therapy:
Now that we've established a base understanding of why collagen is essential as we age, let's look at the most groundbreaking and natural way to effectively generate more collagen in your body using the anti-aging effect of LED light therapy. Proven by research, the red and near-infrared wavelengths utilized in the Celluma SERIES of LED light therapy devices combat the signs of aging. These specific wavelengths of light energy are clinically verified to enhance your body's natural ability to generate collagen and elastin by activating the fibroblast cells. No prescriptions. No medications. No injections. No surgery. Just safe, natural wavelengths of effective, proven light energy.

Boost Collagen Production Cells:
Let’s quickly run through two biology basics: the Krebs Cycle and Adenosine
Triphosphate (ATP). .


  1. The Krebs cycle is what generates cellular energy inside your body. Light activation boosts the body’s natural Krebs Cycle which in turn assists in creating more ATP.

  2. ATP is the energy currency of all the cells in your body. When your body has sufficient ATP levels, then it has more energy to spend on restorative processes such as collagen and elastin production – these are the proteins your body uses to heal itself.

In summary: Light Therapy = Enhanced Krebs (energy) Cycle = Greater ATP Availability = More Collagen

When all of those important metabolic events are happening, it then results in
greater outcomes beyond just collagen production. We see a cascade of benefits
such as:
• Cell generation to replace old cells (mitosis)
• Reduction and prevention of cell death (apoptosis)
• Neurogenesis (new neurons)
• Development of new capillaries (angiogenesis)
• Increased blood flow
• Enhanced Nitric Oxide production

The synergistic effect is that your body is optimized to heal itself. Skin rejuvenation and the reduction of wrinkles and fine lines.

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